THE FACT ABOUT NAD+ SUPPLEMENTATION AND MITOCHONDRIAL HEALTH THAT NO ONE IS SUGGESTING

Subsequent, we handled cells with distinctive concentrations of NAD+. When added for 24 h at 80 µM in HeLa and 400 µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Extended Details Fig. 1k,l). Furthermore, 16 µM of NAD+ was sufficient to lessen fork velocity by ~forty% in HeLa cells without having impacting the total